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Biologics/Immunotherapy News
Infections after AIT injections remain unrelated to treatment
Researchers found no skin and soft tissue infection or systemic infections after administering more than 130,000 allergen immunotherapy treatments to patients at Massachusetts General Hospital and Brigham and Women’s Hospital, according to a recent study published in The Journal of Allergy and Clinical Immunology.
Concomitant SCIT tablet during AIT appears safe, tolerable
Use of a grass sublingual immunotherapy tablet concomitantly with subcutaneous or sublingual immunotherapy appeared safe and tolerable in patients undergoing allergy immunotherapy, according to recent research.
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Modifiable risk factors should be observed for SCIT, SLIT patients
Although the mortality rate for patients undergoing subcutaneous immunotherapy has decreased, researchers still recommend careful selection for patients with modifiable risk factors, according to recent research.
Low level of systemic reactions reported among patients with SCIT
Patients who underwent subcutaneous immunotherapy experienced a low frequency of systemic reactions, but researchers recommended determining predisposing factors to reactions before implementing immunotherapy, according to recent research.
MILES: Viaskin milk allergy patch safe for children
LOS ANGELES — Jonathan M. Spergel, MD, PhD, chief of the allergy section at the Children’s Hospital of Philadelphia, outlined results of the multicenter MILES trial, which indicated that Viaskin Milk Epicutaneous Immunotherapy was well tolerated by patients aged two to 17 years with an IgE-mediated cow’s milk protein allergy.
New immunotherapy threshold may protect against accidental exposure in peanut-allergic individuals
LOS ANGELES — Joseph L. Baumert, PhD, from the Food Allergy Research and Resource Program, at the University of Nebraska-Lincoln, discusses safety benefits linked to increased clinical peanut thresholds through immunotherapy.
Current allergen SCIT practices linked to higher rate of systemic reactions in children
LOS ANGELES — A higher rate of systemic reactions in pediatric patients is associated with subcutaneous immunotherapy, according to recent study data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
Universal policy for autoinjectable epinephrine feasible
LOS ANGELES — A universal policy requiring patients to have autoinjectable epinephrine with them while receiving subcutaneous immunotherapy will enhance safety, according to a recent study presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
Dosage escalation of SCIT safe, tolerable
Patients who received an escalated dosage of subcutaneous immunotherapy across a decreased number of weekly injections tolerated the escalation well with a good safety profile, according to results from an open label phase 2 trial.
SCIT reduces grass pollen allergies in elderly patients
Subcutaneous immunotherapy is effective in treating the symptoms of seasonal allergy rhinitis and grass pollen allergies in the elderly, according to recent research.
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