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Biologics/Immunotherapy News
Astegolimab fails to improve atopic dermatitis outcomes compared with placebo
Although treatment was well tolerated, astegolimab did not effectively improve primary or secondary outcome measurements in atopic dermatitis, according to a study published in The Journal of Allergy and Clinical Immunology.
Peanut OIT appears safe across trials with different eligibility requirements
Two trials that did not require oral food challenges to qualify participants for oral immunotherapy for peanut allergies achieved safety profiles that resembled those of earlier trials using these challenges, according to a study.
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Q&A: Sublingual immunotherapy viable for treating respiratory allergy in children
Sublingual immunotherapy does more than relieve symptoms of respiratory allergy in children. It also modifies the disease, according to a review published in Allergy and Asthma Proceedings as part of its Allergen Immunotherapy (AIT) Primer.
Patients using immunotherapy for allergy report satisfaction with providers
The use of immunotherapy among patients with multiple allergies and comorbidities not only is prevalent, but it also is linked to higher satisfaction with health care professionals, according to a survey conducted by Health Union.
Single-dose immunotherapy improves outcomes among patients with cat allergies
A single dose of immunotherapy treatment prevented reductions in FEV1 among patients with cat allergies and mild asthma, according to a study published in The Journal of Allergy and Clinical Immunology.
Biologic therapy for atopic disease appears safe during pregnancy, more research needed
The use of biologics to treat atopic disease before and during pregnancy does not seem to negatively affect maternal or fetal outcomes, according to a review published in The Journal of Allergy and Clinical Immunology: In Practice.
Blocked IgE-mediated allergen presentation plays role in cow’s milk oral immunotherapy
OIT for cow’s milk allergy may succeed when IgE-mediated allergen presentation is blocked due to a blockage of antibodies, according to a study published in Annals of Allergy, Asthma & Immunology.
Most patients escalated to asthma biologics did not adhere to prior maintenance treatment
About two-thirds of patients who began biologics for asthma exacerbations had suboptimal adherence to maintenance medication in the prior year, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.
Meet the Board: Emma Guttman-Yassky, MD, PhD
“It’s a very exciting time in inflammatory skin diseases,” Emma Guttman-Yassky, MD, PhD, told Healio.
Tralokinumab improves patient-reported outcomes for atopic dermatitis
Tralokinumab led to early and clinically meaningful improvements in patient-reported outcomes for moderate to severe atopic dermatitis compared with placebo, according to a study published in Annals of Allergy, Asthma & Immunology.
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