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Biologics/Immunotherapy News
Immunological profile changes reflect milk oral immunotherapy outcomes
Baseline and long-term milk component immunoglobulin profiles differed among children based on their responses to milk oral immunotherapy and long-term milk consumption, according to a study published in Allergy.
Experts debate the role of biologics in asthma treatment
NASHVILLE, Tenn. — Experts found both consensus and contention during a roundtable discussion of the use of biologics to treat severe asthma, modelled on the ESPN program “Pardon the Interruption,” during the CHEST Annual Meeting.
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Dupilumab leads to sustained improvements in asthma exacerbations, lung function
NASHVILLE, Tenn. — Patients with type 2 inflammatory asthma experienced sustained, long-term reductions in exacerbations and improvements in FEV1 with dupilumab, according to a presentation at the CHEST Annual Meeting.
Dupilumab demonstrates long-term safety, efficacy among children with asthma
NASHVILLE, Tenn. — Children aged 6 to 11 years with uncontrolled, moderate to severe type 2 asthma experienced clinical improvements with dupilumab through a 2-year study period, according to a presentation at the CHEST Annual Meeting.
Biologics for asthma, atopic dermatitis associated with reduced COVID-19 vaccine responses
NASHVILLE, Tenn. — Patients on biologic therapies for severe asthma or atopic dermatitis had lower pseudovirus neutralization 6 months after receiving the second dose of mRNA COVID-19 vaccines, according to a study presented at CHEST 2022.
Combination of allergen immunotherapy, tezepelumab relieves nasal symptoms of cat allergy
The addition of tezepelumab to subcutaneous allergen immunotherapy for 1 year improved results in nasal allergen challenges for patients with cat allergies, according to a study published in The Journal of Allergy and Clinical Immunology.
Allergen immunotherapy improves disease severity in atopic dermatitis
Subcutaneous and sublingual immunotherapy for aeroallergens improved disease severity and quality of life among patients with atopic dermatitis, according to a review published in The Journal of Allergy & Clinical Immunology.
Subcutaneous immunotherapy not linked to severe reactions in severe asthma
Patients with severe asthma who are on subcutaneous immunotherapy for allergy treatment do not experience an increased risk for moderate to severe systemic reactions, according to a study published in Annals of Allergy, Asthma & Immunology.
Q&A: Severe asthma treatment with biologics remains safe during COVID-19 pandemic
Patients who received biologic treatment for asthma did not experience higher SARS-CoV-2 infection rates than the general population, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.
Biomarkers predict effectiveness of dupilumab treatment for moderate to severe asthma
Elevated baseline levels of type 2 biomarkers predicted improved lung function and reduced exacerbation rates with dupilumab among patients with asthma, according to a study in The Journal of Allergy and Clinical Immunology: In Practice.
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