Therapeutic Neurostimulation Updates for Dry Eye Disease: Rapid Response From Chicago
This activity is supported by an educational grant from Alcon Vision, LLC.
Overview
Provider Statement
This continuing education activity is provided by 
Support Statement
This activity is supported by an educational grant from Alcon Vision, LLC.
Activity Description
Dry eye disease (DED) is a chronic condition that affects the tear film and ocular surface, causing persistent discomfort and visual disturbances—which can affect a patient’s daily activities and overall quality of life. Treatment options for DED symptoms include eye drops, gels, implants, lenses, and/or mechanical procedures that aim to promote and/or retain moisture on the ocular surface. Neurostimulation provides a relatively novel mechanism for promoting tear production through activation of the underlying nerve pathways via mechanical, chemical, or electrical stimuli. At present, 2 neurostimulation agents are approved for treatment in patients with DED, including an extranasal stimulation device and a nasal spray (varenicline), and clinical investigation is underway for additional mechanical and electrical devices and novel pharmacologic agents, including AR-15512 and simpinicline. As neurostimulation therapies continue to emerge and play an increasing role in DED management, it is crucial for clinicians to stay updated on the latest data to ensure timely, evidence-based treatment decisions. This Rapid Response activity includes coverage of the latest data on neurostimulation agents for DED management from a recent ophthalmology conference that took place in Chicago, October 2024.
Target Audience
The intended audience for this activity is ophthalmologists and optometrists involved in the management of patients with DED.
Learning Objectives
Upon successful completion of this activity, participants should be better able to:
- Explain the rationale for targeting neuronal pathways for treatment of patients with DED.
- Evaluate the latest clinical data on neurostimulation therapies for DED and their potential roles in treatment.
Activity Chair
Marjan Farid, MD
Clinical Professor of Ophthalmology
Director of Cornea, Cataract and Refractive Surgery
Gavin Herbert Eye Institute
University of California, Irvine
Irvine, CA
Faculty
Cecelia Koetting, OD, FAAO, DipABO
Assistant Professor
University of Colorado School of Medicine
Department of Ophthalmology
Denver, CO
Jennifer M. Loh, MD
Medical Director, Loh Ophthalmology Associates
Board Member, Eye Physicians of Florida
Clinical Faculty, Larkin Hospital Ophthalmology Residency
Miami, FL
Planner/Reviewer
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Accreditation
In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. This activity will also award credit for optometry (COPE) if the requirements necessary for credit are met.
Credit Designation
Vindico Medical Education designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Vindico Medical Education designates this enduring activity for a maximum of 0.75 COPE credit hours. Optometrists should claim only the credit commensurate with the extent of their participation in the activity.
COPE Course Number: 96055-TD
COPE Activity Number: 130024
This enduring material is approved for 1 year from the date of original release, January 27, 2025, to January 26, 2026.
How to Participate in This Activity and Obtain CE Credit
To participate in this activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 6 of the 9 posttest questions correctly. If a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate or COPE CE certificate.
Disclosures
Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.
Relationship information is accurate at the time of content development.
Activity Chair and Faculty report the following relevant financial relationship(s)
Marjan Farid, MD
Consultant: AbbVie, Alcon, Aurion, Bausch + Lomb, BioTissue, CorneaGen, Glaukos, Harrow, J&J Vision, Orasis, Tarsus, Viatris, Zeiss
Individual Stocks (publicly traded): Kala
Cecelia Koetting, OD, FAAO, DipABO
Consultant: Alcon, Aldyera, Allergan/AbbVie, Azura, Bausch + Lomb, Blinkjoy, Bruder, Tarsus, Versea, Viatris
Speaker Contracted by Ineligible Company: Allergan/AbbVie, Bausch + Lomb, Tarsus
Independent Research Contractor: Kala
Jennifer M. Loh, MD
Consultant: AbbVie, Alcon, Bausch + Lomb, BioTissue, Bruder, BVI, C. Light Technologies, Dompé, Horizon, J&J Vision, NovaBay, Ocular Science, Sight Sciences, Sun, Tarsus, Thea, Zeiss
Speaker Contracted by Ineligible Company: AbbVie, Alcon, Bausch + Lomb, Sight Sciences, Sun
Independent Research Contractor: Sight Sciences
Stock Options: Ocular Science
Planner/Reviewer reports the following relevant financial relationship(s)
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.
Vindico Medical Education staff report the following relevant financial relationship(s)
No relevant financial relationships to disclose.
Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.
Unlabeled and Investigational Usage
The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.
Copyright Statement
Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2025 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any Vindico Medical Education continuing education activity does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the FDA. All readers and continuing education participants should verify all information before treating patients or utilizing any product.
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