Glaucoma Management: Rising Out of the Darkness and Into the Light With Rho-Kinase Inhibitors

Overview

Provider Statement

This continuing education activity is provided by 

Support Statement

This activity is supported by an educational grant from Alcon Vision, LLC.

Activity Description

Medical management of glaucoma utilizes agents that lower intraocular pressure (IOP) by decreasing aqueous production, reducing episcleral venous pressure (EVP), and/or increasing uveoscleral and trabecular outflow. Improved outcomes for patients with glaucoma can be achieved by engaging Rho-kinase inhibition (ROCKi), often in combination with therapies using complementary mechanisms of action. This monograph focuses on real-world best practices for expanded treatment options beyond the traditional glaucoma therapy mainstays of prostaglandin analogues and β-blockers. Experts in the field review the clinical and real-world data on ROCKi-based regimens for glaucoma, comparing monotherapy and combination therapy approaches for lowering IOP. The authors discuss a clinical case to highlight optimal use of these therapies in practice.

Target Audience

The intended audience for this activity is comprehensive ophthalmologists and other healthcare professionals involved in the management of patients with glaucoma.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

• Define the mechanism of action of Rho-kinase inhibitors to better understand how they reduce IOP and EVP.
• Compare the efficacy of Rho-kinase inhibitors, both as monotherapy and combination therapy, in the management of glaucoma.

Activity Chair

Thomas W. Samuelson, MD
Attending Surgeon
Glaucoma and Anterior Segment Surgery
Minnesota Eye Consultants, P.A.
Adjunct Professor of Ophthalmology
University of Minnesota
Minneapolis, MN

Faculty

Sarah H. Van Tassel, MD
Director, Glaucoma Service
Director, Glaucoma Fellowship
Assistant Professor of Ophthalmology
Weill Cornell Medicine
New York, NY

Medical Writer

Valerie Zimmerman, PhD

Planner/Reviewer

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Accreditation

In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, April 30, 2024, to April 29, 2025.

How to Participate in This Activity and Obtain CE Credit

To participate in this activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 70% of the posttest questions correctly. If a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

The articles in this monograph were composed by medical writer Valerie Zimmerman, based on the presentations of Drs. Samuelson and Van Tassel during a satellite symposium held on January 17, 2024. The monograph has been approved by each of the faculty individually as an accurate representation of their presentations.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Thomas W. Samuelson, MD
Consultant: Aerie, Alcon Surgical, Allergan, Bausch + Lomb/Valeant, Imprimis, Ocuphire, Ripple Therapeutics, Santen, TearClear, Zeiss
Individual Stocks and Stock Options (publicly traded): Ocuphire
*Individual Stocks and Stock Options (privately held): TearClear

Sarah H. Van Tassel, MD
Consultant: AbbVie, Aerie, Alcon, Bausch + Lomb, Thea, Zeiss

*Does not discuss business lines or products of company(ies).

Medical Writer reports the following relevant financial relationship(s)

Valerie Zimmerman, PhD
No relevant financial relationships to disclose.

Planner/Reviewer reports the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2024 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any Vindico Medical Education continuing education activity does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the FDA. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

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Our agent for copyright issues relating to this web activity is as follows:
Vindico Medical Education, LLC
Attn: Faith Bantivoglio
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CE Questions?

Contact us at cme@vindicoCME.com