Getting Under the Skin With GPP: Understanding and Treating a Life-Threatening Dermatologic Disorder

1.00 CME
60 MINS
$0 FEE
SAVE
You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Getting Under the Skin With GPP

Course Information


Release date: December 21, 2023
Expiration date: December 21, 2024
Estimated time to complete activity: 60 minutes

PROVIDER STATEMENT

Integrity

This activity is provided by Integrity Continuing Education, Inc.

DISCLOSURE OF COMMERCIAL SUPPORT

This activity is supported by an independent medical educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.

PROGRAM OVERVIEW

Characterized by severe flares of painful, pruritic, pus-filled blisters, generalized pustular psoriasis (GPP) is a rare dermatologic disorder that many dermatologists have never seen…at least not that they realized. Historically thought of as a severe form of plaque psoriasis, recent insights into the pathogenesis of GPP show it to be a distinct immuno-inflammatory disease driven by overactivity of the interleukin (IL)-36 pathway.

Join GPP experts Dr. Mark Lebwohl and Dr. Boni Elewski to find out what dermatologists and other healthcare professionals need to know about the pathogenesis of GPP, the mechanism of action of IL-36 receptor antagonists, and how to recognize, diagnose, and manage patients with this inflammatory cutaneous disease.

TARGET AUDIENCE

This educational activity is designed for dermatologists and other healthcare professionals involved in the management of rare dermatologic conditions such as GPP, including primary care physicians, nurse practitioners, and physician assistants.

LEARNING OBJECTIVES

Upon completion of this educational activity, participants should be able to:

  • Identify patient characteristics, common comorbidities, and frequently observed triggers that should raise the index of suspicion for GPP and lead to a timelier diagnosis
  • Describe the pathogenesis of GPP and the mechanism of action of IL-36 receptor antagonists
  • Incorporate new and emerging IL-36 receptor inhibitors to treat and prevent GPP flares based on recent clinical trial findings
  • Develop a multidisciplinary, patient-centric strategy to address the cutaneous and extracutaneous disease burden of GPP

FACULTY

Elewski Faculty Headshot
Boni Elewski, MD
Professor and Chair
James Elder Endowed Professor of Graduate Medical Education
Department of Dermatology
Heersink School of Medicine
University of Alabama
Birmingham, Alabama

Lebwohl Faculty Headshot
Mark Lebwohl, MD
Dean for Clinical Therapeutics
Icahn School of Medicine at Mount Sinai
Professor and Chairman Emeritus
Kimberly and Eric J. Waldman Department of Dermatology
New York, New York

DISCLOSURE OF CONFLICTS OF INTEREST

Integrity Continuing Education, Inc. requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any financial relationships with ineligible companies. All identified relevant financial relationships are thoroughly vetted by Integrity Continuing Education, Inc. for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. All relevant financial relationships have been mitigated.

The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity:

Boni Elewski, MD
Research: AbbVie, AnaptysBio, Boehringer Ingelheim, Bristol Myers Squibb, Incyte, Janssen, Leo, Lilly, Novartis, Pfizer, UCB
Consulting: Amgen, Arcutis, Boehringer Ingelheim, Bristol Myers Squibb, Janssen, Leo, Lilly, Novartis, Ortho Dermatologics, UCB

Mark Lebwohl, MD
Research: AbbVie, Amgen, Arcutis Biotherapeutics, Inc., Avotres, Boehringer Ingelheim, Cara Therapeutics, Dermavant Sciences, Eli Lilly, Incyte, Inozyme, Janssen Research & Development, LLC, Ortho Dermatologics, Pfizer, Sanofi Regeneron, UCB
Consulting: Almirall, AltruBio, Inc., AnaptysBio, Arcutis Biotherapeutics, Inc., AstraZeneca, Avotres Therapeutics, Brickell Biotech, Boehringer Ingelheim, Bristol Myers Squibb, Castle Biosciences, Celltrion, Corevitas, Dermavant Sciences, EPI Health, Evommune, Inc., Facilitation of International Dermatology Education, Forte Biosciences, Foundation for Research and Education in Dermatology, Galderma, Genentech, Incyte, LEO Pharma, Meiji Seika Pharma, Mindera, Pfizer, Seanergy, Strata, Trevi, Verrica

The Integrity Continuing Education, Inc. planners and managers do not have any financial relationships or relationships to products or devices with ineligible companies.

DIRECTIONS TO LEARNER

There are no fees for participating and receiving CME credit for this activity. During the period of December 15, 2023 through December 15, 2024, participants must:

  • Read the learning objectives
  • Complete the pretest
  • Study the educational activity
  • Complete the posttest and the evaluation form

A statement of credit will be issued only upon receipt of a completed posttest with a score of 62% or better and a completed activity evaluation form.

ACCREDITATION STATEMENT

ACCME logo
Integrity Continuing Education, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION

Integrity Continuing Education, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CONTACT INFORMATION

For information about ACCME accreditation of this activity, please contact Integrity Continuing Education, Inc. at (855) 835-4004 or cme@integrityce.com.

DISCLOSURE OF UNLABELED USE

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity Continuing Education, Inc. does not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

MEDIA

Internet

PRIVACY POLICY

When you register or participate in an educational activity sponsored by Integrity Continuing Education, Inc. (Integrity CE), you will be asked for your name, degree(s), affiliation(s), street address, telephone number, fax number, and… (continued)

MINIMUM SYSTEM REQUIREMENTS

Minimum Processor: Intel Pentium 4, 2.33 + GHz (or equivalent)
Operating Systems: Windows XP, Windows 2000, Windows Vista, Windows 7, Windows 10, and Mac OS
Plug-in: Adobe® Flash® Player 10
• Adobe® Flash® Player 10 plug-in should be downloaded
• Click on the “Agree and install now” button after unchecking the optional McAfee Security Scan Plus
For optimal performance, the use of Internet Explorer below 8 is not recommended

For a full listing of recommended operating systems, browsers, and system configurations, please click on the link below:
Click here for more information on minimum system requirements

DISCLAIMER

The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.