Statin Therapy

Triglycerides are a form of lipid ester that contain glycerol and three fatty acids. There are many types of triglycerides, and they play an important role in metabolism.

The coronary artery calcium score enhances clinical risk stratification for patients at risk for atherosclerotic coronary disease.

HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol.

Low density lipoprotein (LDL) is one of several lipoprotein particles that transport cholesterol (a lipophilic molecule) through the aqueous environment of the blood. Other cholesterol carriers include high-density lipoprotein (HDL), very low density lipoprotein (VLDL) and chylomicrons. [Huff 2020;1b; Grundy 2018;7a]

The drugs fenofibrate and gemfibrozil are considered fibric acid derivatives. They can reduce serum triglycerides by as much as 50% in some studies.

Ezetimibe is a nonstatin low-density lipoprotein cholesterol-lowering small molecule drug.

Cardioselective beta-blockers act on beta-1 more than beta-2 and thus will not trigger or worsen asthma as much as non-cardioselective beta-blockers.