Infective Endocarditis

In infective endocarditis, Roth’s spots are seen on retinal exam as retinal hemorrhages with a pale center.

Osler’s nodes occur in the setting of infective endocarditis and represent immune complex deposition.

Janeway lesions can be seen in the setting of infective endocarditis and are small erythematous nodules on the palms of the hands or soles of the feet.

Aortic regurgitation can result from abnormalities of the aortic valve leaflets, dilation of the aortic root, or a severe increase in afterload.