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DEFINITE Trial
Summary: Evaluated implantable cardioverter defibrillators (ICDs) versus none in patients with non-ischemic cardiomyopathies, EF < 35% and premature ventricular contractions or non-sustained ventricular tachycardia. The primary endpoint of reduction of sudden cardiac death was significantly reduced.
Original Publication:
N Engl J Med. May 2004;20;350(21):2151-8.
Eponym: DEFibrillators In NonIschemic Cardiomyopathy Treatment Evaluation