DEFINITE Trial

Summary: Evaluated implantable cardioverter defibrillators (ICDs) versus none in patients with non-ischemic cardiomyopathies, EF < 35% and premature ventricular contractions or non-sustained ventricular tachycardia. The primary endpoint of reduction of sudden cardiac death was significantly reduced.

Original Publication:

N Engl J Med. May 2004;20;350(21):2151-8.

Eponym: DEFibrillators In NonIschemic Cardiomyopathy Treatment Evaluation