The treatment for MAT is directed at the underlying disorder causing the rhythm, usually severe lung disease. If the heart rate needs to be controlled in MAT, verapamil is the preferred pharmacologic therapy.

Multifocal atrial tachycardia (MAT) is a rhythm that frequently occurs in the setting of severe lung disease. MAT is characterized by three different P wave morphologies within one 10 second 12-lead ECG at a heart rate > 100 beats per minutes. This indicates multiple irritable foci generating atrial electrical activity.