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Kevin M. Pantalone, DO, ECNU, FACE

Pantalone is the director of diabetes initiatives and a staff endocrinologist in the department of endocrinology at the Cleveland Clinic.

Most recent by Kevin M. Pantalone, DO, ECNU, FACE

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April 14, 2025
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Once-weekly insulin icodec plus CGM improves glycemic control in type 2 diabetes

Once-weekly insulin icodec plus CGM improves glycemic control in type 2 diabetes

Once-weekly basal insulin combined with an intermittently scanned continuous glucose monitor reduced HbA1c and improved time in range for adults with type 2 diabetes, researchers reported.

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January 08, 2024
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Combination insulin icodec and semaglutide cuts HbA1c and body weight in type 2 diabetes

Combination insulin icodec and semaglutide cuts HbA1c and body weight in type 2 diabetes

Once-weekly combination therapy of basal insulin icodec and semaglutide was noninferior to insulin glargine plus insulin aspart for lowering HbA1c among adults with type 2 diabetes, according to topline results from a phase 3a trial.

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February 01, 2022
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Teach-back method improves interactions between physicians, patients with diabetes

Teach-back method improves interactions between physicians, patients with diabetes

Among patients with diabetes, the teach-back method was associated with better interactions with health care providers, more engagement in shared decision-making and a greater likelihood of receiving lifestyle advice, data show.

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February 26, 2021
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Prediabetes diagnosis poor predictor of disease progression for older adults

Prediabetes diagnosis poor predictor of disease progression for older adults

Older adults with an HbA1c in the prediabetes range were far more likely to revert to normoglycemia or die during 5-year follow-up than to progress to overt type 2 diabetes, according to a community-based study.

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October 27, 2020
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Current, novel combination therapies provide additive benefits for treatment of diabetes

Current, novel combination therapies provide additive benefits for treatment of diabetes

Prescribing combination therapy to individuals with diabetes early in treatment could allow for better glycemic control and reduced odds of treatment failure, according to a speaker at the virtual Cardiometabolic Health Congress.

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September 24, 2020
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DAPA-CKD: Dapagliflozin prolongs survival in CKD with, without type 2 diabetes

DAPA-CKD: Dapagliflozin prolongs survival in CKD with, without type 2 diabetes

Treatment with dapagliflozin significantly reduced renal failure, cardiovascular death or hospitalization for heart failure, and prolonged survival among adults with chronic kidney disease with and without type 2 diabetes, study data show.

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February 04, 2020
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Liraglutide plus metformin may reduce type 2 diabetes risk after gestational diabetes

Liraglutide plus metformin may reduce type 2 diabetes risk after gestational diabetes

Adding liraglutide to metformin may help reduce the risk for developing type 2 diabetes vs. metformin alone for women with gestational diabetes, according to findings published in the Journal of Diabetes and its Complications.

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January 06, 2020
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Addition of linagliptin to metformin reduces prediabetes progression

Addition of linagliptin to metformin reduces prediabetes progression

Prediabetes was less likely to progress to type 2 diabetes among adults who took a combination of linagliptin and metformin vs. metformin alone; the combination group was also more likely to achieve normal glucose levels, according to findings published in Metabolism.

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November 13, 2019
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Diabetes more effectively treated with immediate sitagliptin, metformin combination therapy

Diabetes more effectively treated with immediate sitagliptin, metformin combination therapy

Insulin is needed less frequently and HbA1c is lowered more robustly when adults with type 2 diabetes do not delay combination therapy but begin treatment by taking sitagliptin and metformin together, according to findings published in Diabetic Medicine.

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October 15, 2019
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Simultaneous combination therapy shows major potential in type 2 diabetes

Simultaneous combination therapy shows major potential in type 2 diabetes

CHICAGO — When treating patients with type 2 diabetes, physicians may have more success if they use simultaneous combination therapy immediately rather than following the traditional stepped-up method of waiting to intensify treatment, according to a speaker at the Cardiometabolic Health Congress.